P1951

Sigma

 

Phalloidin–Tetramethylrhodamine B isothiocyanate

Phalloidin from Amanita phalloides

Synonym:Phalloidin-TRITC
Linear Formula:C62H72N12O12S4
Molecular Weight:1305.57
MDL number:MFCD00278840

Details

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Description

ApplicationFluorescent phallotoxin which may be used to identify filamentous actin.
Biochem/physiol ActionsToxin that binds polymeric F actin, stabilizing it and interfering with the function of actin-rich structures.
Other NotesMixed isomers

Properties

biological sourcePhalloidin from Amanita phalloides
fluorescenceλex 540-545 nm; λem 570-573 nm
storage temp.−20°C

Safety

Personal Protective EquipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard CodesT+
Risk Statements26/27/28
Safety Statements36/37/39-45
WGK Germany2

References

referenceFaulstich, H., et al., Preparation of tetramethylrhodaminyl-phalloidin and uptake of the toxin into short-term cultured hepatocytes by endocytosis. Exp. Cell Res. 144, 73-82, (1983) Abstract
 Waggoner, A. Methods Cell Biol. 30, 449, (1989) Abstract